Platinum(II) compounds bearing bone-targeting group: synthesis, crystal structure and antitumor activity.
نویسندگان
چکیده
Platinum(II) complexes bearing geminal bisphosphonate moieties have excellent solubility in both organic and aqueous solutions and show considerable cytotoxicity against human osteosarcoma (MG-63) and ovarian cancer (COC1) cell lines with different apoptotic pathways from that of cisplatin.
منابع مشابه
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عنوان ژورنال:
- Chemical communications
دوره 46 8 شماره
صفحات -
تاریخ انتشار 2010